Tenascin C - Wikipedia
Tenascin C is an oligomeric glycoprotein composed of individual poly peptides with molecular weights ranging from 180 to ~300kDa. The Tenascin family of proteins shares a similar …
Tenascin-C at a glance
First described as a modulator of cell adhesion, tenascin-C also directs a plethora of cell signaling and gene expression programs by shaping mechanical and biochemical cues within the …
Advances in tenascin-C biology - PMC
Abstract Tenascin-C is an extracellular matrix glycoprotein that is specifically and transiently expressed upon tissue injury. Upon tissue damage, tenascin-C plays a multitude of different …
Qual a importância das tenascinas na fisiopatologia de diversas …
May 27, 2024 · Each type of Tenascin is related to specific disorders. Tenascin X is involved in triggering collagen diseases, while types C and W stand out in situations of trauma, …
Tenascin C - an overview | ScienceDirect Topics
Tenascin-C is defined as a glycoprotein that is part of the tenascin family, predominantly present in the extracellular matrix during embryogenesis, bone remodeling, and inflammation, but …
Tenascin-C: From Discovery to Structure-Function Relationships
Nov 26, 2020 · Tenascin-C was discovered a second time due to its appearance in the developing vertebrate musculoskeletal system. Chiquet and Fambrough (5) aimed at finding …
BDTD: A Tenascina-C e a sinalização celular na diferenciação
No estado de aderência intermediária, induzido por proteínas matricelulares, as células tendem a se diferenciar, migrar e proliferar. A tenascina-C é uma proteína matricelular amplamente …
Tenascin-C at a glance - The Company of Biologists
Dec 1, 2016 · ABSTRACT Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein …
Tenascin-C: Form versus function - PMC
We focus on both post transcriptional and post translational events such as splicing, glycosylation, assembly into a 3D matrix and proteolytic cleavage, highlighting how these modifications are …
Tenascin-C targeting strategies in cancer - ScienceDirect
Jun 1, 2024 · Tenascin-C (TNC) is a matricellular and multimodular glycoprotein highly expressed under pathological conditions, especially in cancer and chronic inflammatory diseases.