Scientists have uncovered a gut-specific epigenetic aging mechanism that links inflammation and iron imbalance to cancer risk and may be reversible.

Bowel cancer risk is influenced by several overlapping factors including age, weight and inflammation. This study is early stage biology, but it strengthens the idea that long term gut health is ...

Research led by Weill Cornell Medicine provides new evidence that most colorectal cancers begin with the loss of intestinal stem cells, even before cancer-causing genetic alterations appear. The ...

Although the gut renews itself constantly, its stem cells accumulate age-related molecular changes that quietly alter how ...

The human small intestine is an essential organ that helps us absorb nutrients and vitamins from food. It is an average of 6 meters long and is covered with millions of villi that are separated by ...

The study, “A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts,” was published in Immunity. The team, led by Carlene L. Zindl, Ph.D., found that IL-22 ...

Chemical and Biological Engineering PhD student Max Yavitt is the lead author on a new paper in Science Advancesthat focuses on intestinal tissue research. The work could allow researchers to control ...

Two independent studies by Columbia scientists suggest that research into the gut’s stem cells over the past 15 years has been marred by a case of mistaken identity: Scientists have been studying the ...

As people live longer, the gut quietly accumulates damage that can tip the balance between healthy tissue renewal and chronic disease. Researchers have now traced a key part of that shift to specific ...