"Medical Journeys" is a set of clinical resources reviewed by physicians, meant for the medical team as well as the patients they serve. Each episode of this 12-part journey through a disease state ...

The first description of a particular melanocytic nevus found in relatives from six cases of melanoma was made in 1978. [1] Although initially coined B-K moles, these moles soon acquired the name ...

Childhood melanoma, while rare, represents the most prevalent form of skin cancer among pediatric populations. Among its various subtypes, Spitz tumors are of particular interest due to their distinct ...

Most specialists can't spot the difference between a Spitz nevus and a melanoma lesion. Atypical Spitz tumors are associated with a good prognosis, but spitzoid melanoma can be deadly, a 10-year ...

Melanocytic nevi are a category of benign melanocytic proliferations with a number of subtypes. These include congenital melanocytic nevi, blue nevi, acquired melanocytic nevi, and Spitz nevi. Many of ...

DNA methylation is the most well-studied epigenetic modification in cancer biology. 5-hydroxymethylcytosine is an epigenetic mark that can be converted from 5-methylcytosine by the ten-eleven ...

Melanoma is rare in children. However, the clinical features of the disease in this population have been well-documented through single-institution experiences and population-based analyses. Still, ...

Moles are more than a sometimes unsightly skin growth. Most harbor mutations that can trigger deadly skin cancer--melanoma--and most fair-skinned humans have at least 10 such moles. Yet, only one in ...

Melanoma in children is a rare entity. Based on 2006–2010 SEER data, it is estimated that melanoma accounts for approximately 2% of all malignances in patients younger than 20. 1 The majority of these ...