Findings in Nature Genetics support the idea that balance between sodium and potassium are essential to the heart. An international group of scientists identified 10 genes connected to changes in QT ...

Baltimore, MD - A large-scale genomic study has identified a new gene associated with abnormal QT intervals. The gene, known as NOS1AP, was not previously known to modulate cardiac repolarization, but ...

Objective: To assess health care practitioners' ability to correctly measure the QT interval, and to identify factors and medications that may increase the risk of QT-interval prolongation and ...

A heart arrhythmia is when your heart beats too fast, too slow, or out of sync. Some arrhythmias can be genetic. A genetic arrhythmia happens when one or both of your parents pass down a gene change ...

Congenital long QT syndrome (LQTS) is caused by mutations in genes encoding cardiac ion channels, and is characterized by prolongation of the ventricular cardiac action potential, which lengthens the ...

The QT interval is the time from the beginning of the QRS complex, representing ventricular depolarization, to the end of the T wave, resulting from ventricular repolarization. The normal QT interval ...

QT prolongation occurs when the heart muscle takes longer to contract and relax than usual. It can affect heart rhythms and lead to sudden cardiac arrest. The heart is a muscle that contracts and ...

The ECG findings of hyperkalemia change as the potassium level increases. From earliest to latest, the ECG findings include: Peaked T waves best seen in the precordial leads, shortened QT interval and ...

One of the principal tasks of an oncologist is to determine whether to administer, reduce the dose, or hold chemotherapy on the basis of patient characteristics, organ function, and toxicities. These ...

Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA Correspondence to Dr M J Ackerman, Long QT Syndrome Clinic and the Mayo Clinic Windland Smith ...

Arsenic trioxide (ATO) is a highly effective agent for the treatment of acute promyelocytic leukemia (APL). QT interval prolongation is common with ATO and can pose a barrier to effective ...