Seattle rushed for a season-high 180 yards winning at San Francisco Jan. 3. The Niners used single-high and two-deep safeties. Now what?

Jason Ence breaks down his favorite Seahawks vs. 49ers anytime touchdown picks ahead of Saturday's NFC West showdown.

Including the postseason, the Seahawks lead the overall series 32-24. The 49ers will look to draw the record closer to their favor with a road victory on Saturday night. Let’s look back at the two playoff matchups.

The Seattle Seahawks have pulled off a historic rally and pulled into first place in the NFC. After throwing a touchdown pass to Jaxon Smith-Njigba, Sam Darnold delivered a game-winning two-point conversion pass to little-used tight end Eric Saubert to defeat the Los Angeles Rams, 38-37, in overtime in an instant classic.

THE SEAHAWKS JUST DEFEATED THE LOS ANGELES RAMS! Relive the game of the year with our concluded live blog. Sam Darnold found Jaxon Smith-Njigba for a touchdown, decided to go for two points, and won by finding Eric Saubert! Seattle now controls their own destiny for the No. 1 seed in the NFC!

Colby Parkinson, now a tight end for the Los Angeles Rams, made a spinning, game-winning sideline touchdown catch in a 34-31 victory over the Carolina Panthers in Charlotte. Parkinson caught the pass near the sideline as he spun around and darted two more yards for the 19-yard touchdown reception from quarterback Matthew Stafford.

The Indianapolis Colts visit the Seattle Seahawks in NFL Week 15 action: Live updates, score, highlights, Philip Rivers stats.

There’s a lot going on this Saturday against the 49ers, so you might have not noticed AJ Barner making his own play for franchise history, of sorts. When I was a little kid, it was Christian Fauria, who never had over 400 yards in a season and ended up ...

USA TODAY Sports examines the winners and losers from Saturday night's NFC West showdown as the Seattle defense held San Francisco in check.