Current evidence suggests that CIC are involved in the pathogenesis of HSP, and several studies have demonstrated both IgA and IgG containing CIC in patients with HSP. Recent work from this laboratory ...
Rheumatoid factor (RF), particularly IgM RF, may play an important role in the pathogenesis of rheumatoid arthritis. IgG and IgA have been reported. In children with juvenile rheumatoid arthritis (JRA ...
When persistent joint pain strikes, the search for answers often leads to a crucial diagnostic tool: the rheumatoid factor test. This relatively quick blood analysis serves as a window into the immune ...
Seronegative rheumatoid arthritis is a real condition where individuals have RA symptoms but test negative for rheumatoid factor (RF) and cyclic citrullinated peptides (CCP). Individuals with RA ...
Autoantibodies to IgG/HLA class II complexes are associated with rheumatoid arthritis susceptibility
Specific HLA class II alleles are strongly associated with susceptibility to rheumatoid arthritis (RA); however, how HLA class II regulates susceptibility to RA has remained unclear. Recently, we ...
Rheumatoid arthritis is a common autoimmune disease that is associated with progressive disability, systemic complications, early death, and socioeconomic costs. 1 The cause of rheumatoid arthritis is ...
Diagnosing rheumatoid arthritis involves a comprehensive approach, as there isn’t a single definitive test. Instead, doctors use a combination of blood tests, physical assessments, joint scans, and ...
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