In this free webinar, learn backbone protecting group strategies for overcoming difficulties during solid-phase peptide synthesis and solution-phase handling. The featured speakers will share tips and ...
Proteins carry out exceptionally diverse molecular functions—even though they are all built on an unvarying polyamide backbone. How much more chemical diversity might be unlocked by editing that ...
The P99 beta lactamase peptide backbone is shown in complex with a beta lactam substrate (PDB file 4KEN), which is rendered as a stick figure with carbon in cyan, nitrogen in dark blue, oxygen in red, ...
A relatively simple peptide modification could unlock a whole class of targets for drug discovery, new research shows. Researchers at the University of Birmingham, in collaboration with the ...
What is it? As the name suggests, nonribosomal peptide synthesis (NRPS) generates polypeptides sans ribosome. The resultant peptides, generally short oligomers of two to perhaps 48 residues, are not ...
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