Loss of GATA6-a transcription factor that controls which genes are turned on or off-can reprogram colorectal cancer cells ...

A newly identified loss of cellular identity may enable colorectal cancer cells to enter a highly flexible state that promotes liver metastasis.

Researchers found that loss of GATA6 reprograms colorectal cancer cells into flexible, fetal-like states that can spread to ...

The Liver Cancer Program at the Icahn School of Medicine at Mount Sinai is situated in New York City, and has been at the forefront of clinical management of HCC in the United States for at least 20 ...

Researchers found that a rare liver cancer evades immunotherapy by luring immune T cells away from the tumor and trapping them in nearby fibrous tissue. An FDA-approved drug called AMD3100 freed those ...

Over the past decade, advances in organoid culturing methods have enabled the growth of three-dimensional cellular cultures in vitro with increasing fidelity with respect to the cellular composition, ...

Liver cancer cells thrive on fat, posing a serious risk of cancer diagnosis for millions of people living with fatty liver disease. But researchers at McMaster University in collaboration with ...

A new ultrasound-guided nanotherapy wipes out liver tumors while training the immune system to keep them from coming back. Study: Sonodynamic biodegradable pseduo-conjugate polymer delivery of ...