Heart disease is still the number one cause of death among adults worldwide. High cholesterol levels are one contributor to heart disease. Researchers have now developed a method that can analyze a ...

An international team led by a University of Pittsburgh School of Medicine scientist has created a first-of-its-kind resource to identify those with a genetic risk for elevated "bad" cholesterol—a ...

An international team led by a University of Pittsburgh School of Medicine scientist has created a first-of-its-kind resource to identify those with a genetic risk for elevated 'bad' cholesterol -- a ...

PHILADELPHIA, PA—For high-risk patients with heterozygous familial hypercholesterolemia (HeFH), a novel therapy that shuts off the PCSK9 gene can lower LDL cholesterol, early data from the heart-1 ...

Heterozygous familial hypercholesterolemia (HeFH) is caused by mutations in the LDL receptor gene, resulting in unusually high levels of low-density lipoprotein (LDL-C) in serum. Researchers from ...

Please provide your email address to receive an email when new articles are posted on . A single-dose CRISPR gene-editing infusion lowered blood PCSK9 in three patients with HeFH and advanced CAD. One ...

A revolutionary gene-silencing technique has shown that a single treatment can dramatically lower LDL cholesterol levels for over a year—without permanently altering DNA. Could this be the future of ...

Heterozygous familial hypercholesterolemia (HeFH) is a genetic disorder a person can inherit from a parent. It can cause a person to develop dangerously high cholesterol levels. HeFH affects how a ...