To uncover the inflammatory pathways involved in cell injury and death, Kenneth Rock at the University of Massachusetts and colleagues injected necrotic cells into mice deficient in various toll-like ...

Using a combination of newly developed methods, researchers led by Ludwig-Maximilians-Universitaet (LMU) in Munich immunologist Veit Hornung have defined a previously unknown pathway that triggers ...

New research co-led by Indiana University School of Medicine scientists has exposed a vulnerability in acute myeloid leukemia ...

A recent multicenter clinical trial has uncovered inflammatory pathways that contribute to asthma flare-ups in children that occur despite treatment, according to findings published in JAMA Pediatrics ...

Aging immune cells may be sabotaging the body from within. Researchers found that macrophages produce a protein that locks ...

Whether reeling from a sudden stroke or buckling under the sustained assault of Alzheimer’s, the brain becomes inflamed, leading to cognitive problems and even death. Scientists have known for many ...

Immune cells called monocytes produce a key inflammatory protein called interleukin-1 beta (IL-1β) through an unconventional pathway in patients with systemic lupus erythematosus, commonly referred to ...

Inflammation can feel like a small storm inside your body. It brings heat, swelling, and pain as the immune system rushes to ...

How does obesity affect insulin production? Researchers are shining light on new stages of the ERK pathway. Researchers at the Tohoku University Graduate School of Medicine have uncovered a key ...

ORLANDO -- Markers of inflammation varied by sex, age, and menopausal status, according to a biomarker analysis. For TNF-α, the association was seen among women regardless of age (P<0.01) and in both ...

Ischemic stroke is a major cause of death and disability, caused by a sudden loss of oxygen supply to the brain due to blocked blood vessels. Recanalization treatments such as intravenous thrombolysis ...