Prostate cancer is characterized by a dependence upon androgen receptor (AR) signaling, and androgen deprivation therapy (ADT) is the accepted treatment for progressive prostate cancer. Although ADT ...

The function of the glycolytic enzyme hexokinase 1 differs depending on its location within the cell, according to a Northwestern Medicine study published in Molecular Cell. The enzyme uses different ...

Three forms of hexokinase activity can be demonstrated in hemolysates of normal human erythrocytes by starch-gel electrophoresis. The similarity of these isoenzymes to Types I, II and III hexokinases ...

A spoonful of sugar may make the medicine go down, but understanding what happens to that sugar in the cell is far more complicated than simple digestion, according to researchers. A spoonful of sugar ...

Researchers have identified a characteristic unique to cancer cells in an animal model of cancer -- and they believe it could be exploited as a target to develop new treatment strategies. Researchers ...

The hexokinase gene family encompasses a group of multifunctional enzymes that are pivotal in both the metabolic and signalling pathways of plants. These enzymes catalyse the phosphorylation of hexose ...

This article shows how enzymatic activity can be effectively determined by means of the Eppendorf BioSpectrometer. The preliminary measurements were carried out by utilizing the “single λ-continuous” ...

A second hexokinase (EC 2.7.1.1) was obtained from pea seed (Pisum sativum L. var. Progress No. 9) extracts. The enzyme, termed hexokinase II, had a high affinity (Km, 48 micromolar) for glucose and a ...

A spoonful of sugar may make the medicine go down, but understanding what happens to that sugar in the cell is far more complicated than simple digestion, according to researchers. For sugars to ...