Bone fracture healing is a dynamic process that relies on coordinated cellular interactions for effective tissue regeneration. We employ optimized spatial transcriptomics to delineate the locations ...

Neutrophils are emerging as an important player in skeletal muscle injury and repair. Neutrophils accumulate in injured tissue, thus releasing inflammatory factors, proteases and neutrophil ...

A new study explores the potential of fibroblast growth factor receptor (FGFR) antagonists in restoring defective mandibular bone repair in mouse models of osteochondrodysplasia, a group of genetic ...

When skin tissue is wounded, our blood starts clotting as part of the healing process. Scientists have now developed a blood-based implant that supercharges this mechanism for bigger repair projects: ...

For patients suffering from traumatic injuries that leave behind "volumetric" gaps—where significant bone and blood vessels ...

A tool made from a modified glue gun can now repair broken bones in surgery by 3D-printing grafts directly onto them. Bone implants have historically been made of metal, donor bone and more recently ...

A new study has shown pollen grains can be used as green templates for producing biomaterials, showcasing their potential to support drug delivery and bone regeneration. With an increasingly aging ...

The first comprehensive single-cell atlas of bone-innervating sensory neurons has identified their dual role in reporting and repairing bone damage, providing a potential target for drugs that might ...

Birmingham researchers have shown that PEPITEM, a naturally-occurring peptide (small protein), holds promise as a new therapeutic for osteoporosis and other disorders that feature bone loss, with ...

Researchers uncover a redox-regulated mechanism that determines whether bone fractures heal or progress to non-union. Bone has an extraordinary capacity to heal after injury, restoring its structure ...

Photomicrograph of dorsal root ganglia (DRG) neurons from a newborn rat. A research team led by Johns Hopkins Medicine has created the first map showing the communication network among DRG neurons in ...

The innovative technology is based on a nanoparticle in the form of a polymer sphere. The sphere introduces a microRNA molecule into cells. This triggers human body cells, located at the site of the ...