Fibrosis, characterized by excessive extracellular matrix accumulation and disrupted tissue architecture, is an area where TB-4 has attracted significant attention. Investigations purport that TB-4 ...

In an unprecedented large-scale study, researchers have mapped out the first molecular events that cause harmful protein buildups in the brain of people with Alzheimer's disease. "By measuring the ...

Researchers use microscopy to chart amyloid beta's underlying structure and yield insight into neurodegenerative disease. Amyloid-beta (A-beta) aggregates are tangles of proteins most notably ...

After studying 140,000 versions of the Aβ42 peptide, scientists identified some of the earliest molecular interactions that drive the formation of harmful amyloid protein aggregates found in Alzheimer ...

The intricate interplay between pancreatic beta cells and glucagon-like peptide-1 (GLP-1) has drawn considerable attention in efforts to improve the diagnosis and treatment of diabetes and insulinomas ...

For patients with immunoglobulin D multiple myeloma (IgD MM), those with renal impairment (RI) have poorer prognosis and shorter median survival than those with no renal impairment (no-RI), according ...

Potentially more than 90% of Alzheimer's disease cases would not occur without the contribution of a single gene (APOE), according to a new analysis led by UCL researchers. In a study led by Lund ...

3D render of a molecular model. The molecule is alanine peptide. The shroud represents the region of hydrophobic repulsion, where the strength of the hydrophobic effect is approximately proportional ...